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Hereditary Cancer Gene Panel – Genetic Testing for Inherited Cancer Risks
Worried about a family history of cancer? The Hereditary Cancer Gene Panel is an advanced genetic test that examines your DNA in depth to uncover inherited cancer risks that may have been silently passed down to you. It helps you understand your personal risk and plan preventative care, so you can take the most effective steps to protect your health – before the disease develops.
Conditions for Undergoing the Test
✅ Who should undergo the test
You should consider testing if ANY of the following apply:
1. Personal cancer history
- Diagnosed with breast, ovarian, fallopian tube, peritoneal, colorectal, endometrial, pancreatic, or prostate cancer before age 50.
- Multiple primary cancers in one person.
- Rare cancers such as male breast cancer.
2. Family history
- First-degree relative (parent, sibling, child) with any of these cancers, especially diagnosed before age 50.
- Two or more relatives with the same or related cancers (e.g., breast–ovarian, colon–endometrial).
- One relative with multiple primary cancers.
3. Known familial gene mutation
- A family member has a known pathogenic mutation such as BRCA1/2 or Lynch syndrome genes (MLH1, MSH2, MSH6, PMS2, EPCAM).
4. High-risk ancestry
- Belong to an ancestry with higher prevalence of hereditary cancer genes, such as Ashkenazi Jewish or other high-risk populations.
❌ Who should not undergo the test
Testing is generally NOT recommended if all of the following apply:
- No personal history of related cancers and no first or second-degree relatives with these cancers.
- Only one family member with cancer diagnosed after age 60.
- No known cancer-related gene mutation in the family.
Note
- Pre and post-test genetic counseling is strongly recommended.
- Individuals not meeting criteria should follow routine age and risk-based cancer screening (e.g., mammogram, colonoscopy).
- Recommended frequency: once in a lifetime.
What is this screening?
This is a screening test for genes associated with hereditary cancers, which account for around 5–10% of all cancer cases. Knowing whether you carry genetic mutations that increase your risk can be a key factor in planning early surveillance and preventative measures.
Service Procedure
- Please make an appointment at least two days in advance via Line @BNHhospital, by email at [email protected], or by calling 02-0220700 ext. 2847, 4445–7 during the hours of 13:00–15:00 only.
- Once your request has been received, the Health Check-up Department will contact you between 13:00–15:00 or by email to confirm your appointment.
- If you need to reschedule, kindly inform us at least two days in advance, again during 13:00–15:00 only.
- The screening service is provided at the Advanced Diagnostic Centre, 4th Floor, Zone A, BNH Hospital. On the day of your visit, our staff will first provide information about the test.
- A blood sample will then be collected without the need for fasting or dietary restrictions.
- The sample will be analysed in the laboratory, with results available in approximately 21 days.
- You will meet with a doctor to review the screening report, which will indicate any potential risk signals for various cancers and guide the planning of further diagnostic examinations
- In cases where a positive result is found, a specialist will provide additional consultation and recommend specific diagnostic procedures.
Frequently Asked Questions (FAQ) about Hereditary Cancer Gene Panel
A: It suits those with a family history of cancer (such as breast, ovarian or colorectal) or who want to know their inherited cancer risk.
A: It uses a blood sample with no fasting required; bring your family health and cancer history.
A: Results are available within a few weeks and show gene mutations that increase cancer risk, for proactive surveillance and prevention.
A: Yes. Physicians and specialists are available to explain your results and next steps. You can book an appointment at BNH Hospital via the website or by phone.
